A Validated Analysis Pipeline for Mass Spectrometry-Based Vitreous Proteomics: Insights Into Proliferative Diabetic Retinopathy

Published in Research Square, 2021

Recommended citation: Sarah R Weber, Yuanjun Zhao, Jingqun Ma et al. A Validated Analysis Pipeline for Mass Spectrometry-Based Vitreous Proteomics: Insights Into Proliferative Diabetic Retinopathy, 27 July 2021, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-721629/v1] https://www.researchsquare.com/article/rs-721629/v1

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Vitreous is an accessible, information-rich biofluid that has recently been studied as a source of retinal disease-related proteins and pathways. However, the number of samples required to confidently identify perturbed pathways remains unknown. In order to confidently identify these pathways, power analysis must be performed to determine the number of samples required.

Recommended citation: Sarah R Weber, Yuanjun Zhao, Jingqun Ma et al. A Validated Analysis Pipeline for Mass Spectrometry-Based Vitreous Proteomics: Insights Into Proliferative Diabetic Retinopathy, 27 July 2021, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-721629/v1]